Pipernonaline

Cat. No. NATM-2505-CXX-173

Package 1 mg/5 mg/10 mg/50 mg

Description

Pipernonaline, a piperine derivative with antiprostate cancer activity, inhibits proliferation of androgen-dependent/independent LNCaP/PC-3 prostate cells. It activates caspase-3 and promotes procaspase-3/PARP cleavage. Pipernonaline also mediates ROS production, increased intracellular Ca2+, and mitochondrial membrane depolarization.

Product Details

Formula	C21H27NO3
Molecular Weight	341.44
SMILES	O=C(N1CCCCC1)/C=C/CCCC/C=C/C2=CC=C(OCO3)C3=C2
Biological Target	Caspase; Apoptosis
Initial Source	Plants; Piperaceae; Piper longum Linn.
Shipping Conditions	Room Temperature
Storage Information	Powder: -80°C, 2 years; -20°C, 1 years. In solvent: -80°C, 6 months; -20°C, 1 month