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RECTAS is a pre-mRNA splice modulator discovered to correct aberrant IKBKAP splicing in familial dysautonomia cells. Combined with phenylbutyric acid, RECTAS restores DJ-1 protein levels and mitochondrial function in Parkinson’s disease models.
Formal Name | 2-Chloro-N-(2-furanylmethyl)-9H-purin-6-amine |
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Purity | >98% |
CAS Number | 101862-47-9 |
Formula | C10H8ClN5O |
Molecular Weight | 249.7 |
Appearance | Powder |
Solubility | Dissolves in DMSO (27 mg/mL) |
Stability | ≥ 2 years |
Application Procedures | First, dissolve in DMSO (27 mg/mL), and then dilute it into an aqueous buffer. Solutions in DMSO can be stored at -20°C for up to 3 months. |
Storage Information | -20°C |
pre-mRNA splicing modulator