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RECTAS

Cat. No. BIAOS-2505-CXX-37

Package 5 mg/25 mg

Datasheet

Description

RECTAS is a pre-mRNA splice modulator discovered to correct aberrant IKBKAP splicing in familial dysautonomia cells. Combined with phenylbutyric acid, RECTAS restores DJ-1 protein levels and mitochondrial function in Parkinson’s disease models.

Product Details

Formal Name 2-Chloro-N-(2-furanylmethyl)-9H-purin-6-amine
Purity >98%
CAS Number 101862-47-9
Formula C10H8ClN5O
Molecular Weight 249.7
Appearance Powder
Solubility Dissolves in DMSO (27 mg/mL)
Stability ≥ 2 years
Application Procedures First, dissolve in DMSO (27 mg/mL), and then dilute it into an aqueous buffer. Solutions in DMSO can be stored at -20°C for up to 3 months.
Storage Information -20°C

Application

pre-mRNA splicing modulator