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An NF-κB inhibitor and anti-inflammatory agent that selectively inhibits LPS- and TNF-α-induced IκBα ubiquitination (IC50 = 3 μM). Inhibits TNF-α, IL-1β, and IL-6 production.
Formal Name | 6-(benzenesulfinyl)tetrazolo[1, 5-b]pyridazine |
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Synonyms | 6-(Benzenesulfinyl)tetrazolo[1, 5-b]pyridazine |
Purity | >95% |
CAS Number | 62645-28-7 |
Formula | C10H7N5OS |
Molecular Weight | 245.26 |
Appearance | Solid |
Stability | Store under desiccating conditions |
Storage Information | -20°C |
NF-kappaB inhibitor