Rutin (Rutoside) hydrate, a flavonoid from many plants, exhibits anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective, and Aβ oligomer reducing activities. It crosses the blood-brain barrier and attenuates vancomycin-induced renal tubular cell apoptosis by suppressing apoptosis, mitochondrial dysfunction, and oxidative stress.
| Synonyms | Rutoside hydrate; Quercetin 3-O-rutinoside hydrate |
|---|---|
| Purity | 98.99% |
| Formula | C27H3O16.36/5H2O |
| Molecular Weight | 713.04 |
| SMILES | O=C1C(O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO[C@H]3[C@@H]([C@@H]([C@H]([C@H](C)O3)O)O)O)O2)O)O)O)=C(C4=CC=C(O)C(O)=C4)OC5=CC(O)=CC(O)=C15.O.[36/5] |
| Appearance | Solid |
| Biological Target | Amyloid-β; Autophagy; Apoptosis; Endogenous Metabolite |
| Initial Source | Plants; other families |
| Solubility | DMSO: 125 mg/mL (175.31 mM, need ultrasonic) |
| Shipping Conditions | Room Temperature |
| Storage Information | Powder: -80°C, 2 years; -20°C, 1 years. In solvent: -80°C, 6 months; -20°C, 1 month |
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