Sanggenon C

Cat. No. NATM-2505-CXX-182

Package 1 mg/5 mg/10 mg/25 mg/50 mg/100 mg/200 mg

Description

Sanggenon C, a flavonoid, protects against cardiac hypertrophy and fibrosis by suppressing the calcineurin/NFAT2 pathway. It induces apoptosis by inhibiting mitochondrial fission via ERK signaling. Sanggenon C also reduces iNOS expression in RAW264.7 cells and TNF-α-stimulated cell adhesion/VCAM-1 expression by suppressing NF-κB. It exhibits antioxidant, anti-inflammatory, and antitumor activities.

Product Details

Purity	98.50%
Formula	C40H36O12
Molecular Weight	708.71
SMILES	C/C(C)=C/C[C@](C1=CC=C(O)C=C1O2)(OC3=CC(O)=C([C@@H](C=C(C)C[C@@H]4C(C=CC(O)=C5)=C5O)[C@@H]4C(C(C=CC(O)=C6)=C6O)=O)C(O)=C3C7=O)[C@]27O
Appearance	Solid
Color	Light yellow to green yellow
Biological Target	Phosphatase; ERK; NF-κB; Apoptosis
Target	NF-κB; ERK
Initial Source	Plants; Moraceae; Morus alba Linn.
Solubility	DMSO: 100 mg/mL (141.10 mM, need ultrasonic)
Shipping Conditions	Room Temperature
Storage Information	-20°C, sealed storage, away from moisture and light