SHMT2 Protein, Human catalyzes serine cleavage to produce 5, 10-methylenetetrahydrofolate for purine synthesis. This tag-free recombinant human SHMT2, expressed in E. coli, binds to mitochondrial DNA and participates in target protein deubiquitination via the BRISC complex.
| Purity | Greater than 90% as determined by reducing SDS-PAGE. |
|---|---|
| Molecular Weight | 52.7 kDa |
| Appearance | Solution |
| Formulation | 50 mM HEPES (pH7.5), 200 mM NaCl, 20% glycerol, 1 mM DTT. |
| Species | Human |
| Source | E. coli |
| Accession | P34897 (S29-H504) |
| Gene ID | 6472 |
| Alternative Names | SHMT2; Serine hydroxymethyltransferase; mitochondrial; SHMT; Glycine hydroxymethyltransferase; Serine methylase |
| Tag | Free |
| Endotoxin Level | <1 EU/μg, determined by LAL method. |
| Shipping Conditions | Dry Ice |
| Storage Information | Store at -80°C for 1 year from the date of receipt. After opening, it's stable at -20°C for 3 months. For extended storage, freeze in aliquots at -80°C. Avoid repeated freeze-thaw cycles. |
Datasheet