SHMT2 Protein, Human (His) catalyzes serine cleavage to produce 5, 10-methylenetetrahydrofolate for purine synthesis. This recombinant human SHMT2, expressed in E. coli with an N-6*His tag, binds to mitochondrial DNA and participates in target protein deubiquitination via the BRISC complex.
| Purity | Greater than 90% as determined by reducing SDS-PAGE. |
|---|---|
| Appearance | Solution |
| Formulation | 50 mM Tris-HCl, pH7.5, 200 mM NaCl, 20% glycerol. |
| Species | Human |
| Source | E. coli |
| Accession | P34897 (S29-H504) |
| Gene ID | 6472 |
| Alternative Names | SHMT2; Serine hydroxymethyltransferase; mitochondrial; SHMT; Glycine hydroxymethyltransferase; Serine methylase |
| Tag | N-6*His |
| Endotoxin Level | <1 EU/μg, determined by LAL method. |
| Shipping Conditions | Dry Ice |
| Storage Information | Stable at -80°C for 1 year or at -20°C for 3 months after opening. For extended storage, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. |
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