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Sideroxylin, a C-methylated flavone from Callistemon lanceolatus, shows antimicrobial activity against Staphylococcus aureus. It inhibits ovarian cancer cell proliferation and induces apoptosis by causing DNA fragmentation, mitochondrial membrane depolarization, and ROS generation.
Formula | C18H16O5 |
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Molecular Weight | 312.32 |
SMILES | O=C1C=C(C2=CC=C(O)C=C2)OC3=C(C)C(OC)=C(C)C(O)=C13 |
Appearance | Solid |
Color | Light brown to brown |
Biological Target | Bacterial; Reactive Oxygen Species; Apoptosis |
Initial Source | Plants; Myrtaceae; Eucalyptus saligna |
Solubility | DMSO: 15.5 mg/mL (49.63 mM, need ultrasonic and warming) |
Shipping Conditions | Room Temperature |
Storage Information | Powder: -20°C, 3 years. In solvent: -80°C, 6 months; -20°C, 1 month |