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Sideroxylin, a C-methylated flavone from Callistemon lanceolatus, shows antimicrobial activity against Staphylococcus aureus. It inhibits ovarian cancer cell proliferation and induces apoptosis by causing DNA fragmentation, mitochondrial membrane depolarization, and ROS generation.
| Formula | C18H16O5 |
|---|---|
| Molecular Weight | 312.32 |
| SMILES | O=C1C=C(C2=CC=C(O)C=C2)OC3=C(C)C(OC)=C(C)C(O)=C13 |
| Appearance | Solid |
| Color | Light brown to brown |
| Biological Target | Bacterial; Reactive Oxygen Species; Apoptosis |
| Initial Source | Plants; Myrtaceae; Eucalyptus saligna |
| Solubility | DMSO: 15.5 mg/mL (49.63 mM, need ultrasonic and warming) |
| Shipping Conditions | Room Temperature |
| Storage Information | Powder: -20°C, 3 years. In solvent: -80°C, 6 months; -20°C, 1 month |