T-Cadinol

Cat. No. NATM-2505-CXX-195

Package 1 mg/5 mg/10 mg/50 mg

Description

T-Cadinol, a sesquiterpene from C. sylvestris, shows anti-Trypanosoma cruzi activity (IC50s: 18.2 μM for trypomastigotes, 15.8 μM for amastigotes). It induces mitochondrial damage in parasites, causing membrane hyperpolarization and reduced reactive oxygen species. T-Cadinol is useful for Chagas disease research.

Product Details

Formula	C15H26O
Molecular Weight	222.37
SMILES	CC([C@H]1[C@@]2([H])[C@](CCC(C)=C2)([H])[C@@](O)(CC1)C)C
Biological Target	Parasite
Initial Source	Plants; Salicaceae; Casearia sylvestris Sw.
Shipping Conditions	Room Temperature
Storage Information	Powder: -80°C, 2 years; -20°C, 1 years. In solvent: -80°C, 6 months; -20°C, 1 month