Tenacissoside C is an anti-cancer compound that inhibits angiogenesis. It induces apoptosis in cancer cells by downregulating anti-apoptotic factors and activating caspase-9 and caspase-3. Tenacissoside C also arrests cancer cell cycles and induces apoptosis via the mitochondrial pathway.
| Formula | C53H76O19 |
|---|---|
| Molecular Weight | 1017.16 |
| SMILES | C[C@@]12[C@]3(CC[C@H]2C(C)=O)[C@]4([C@]([C@@]5([C@@](C[C@H](CC5)O[C@H]6C[C@H]([C@@H]([C@H](O6)C)O[C@H]7[C@@H]([C@@H]([C@@H]([C@H](O7)C)O[C@@H]8O[C@@H]([C@H]([C@@H]([C@H]8O)O)O)CO)OC)O)OC)([H])CC4)C)([H])[C@@H]([C@H]1OC(/C(C)=C/C)=O)OC(C9=CC=CC=C9)=O)O3 |
| Biological Target | Apoptosis |
| Initial Source | Plants; Asclepiadaceae; Marsdenia tenacissima (Roxb.) Moon |
| Shipping Conditions | Room Temperature |
| Storage Information | Powder: -80°C, 2 years; -20°C, 1 years. In solvent: -80°C, 6 months; -20°C, 1 month |
Datasheet