TFAM Protein, Human (His) regulates lymphangiogenesis, interacts with TEK/TIE2 and ITGA5, and binds to the mitochondrial light chain promoter. This recombinant human TFAM, expressed in E. coli with a His tag, is critical for accurate promoter recognition and transcription initiation as part of the mitochondrial transcription initiation complex with TFB2M and POLRMT.
| Purity | Greater than 95 % as determined by reducing SDS-PAGE. |
|---|---|
| Molecular Weight | 30 kDa |
| Appearance | Lyophilized Powder |
| Formulation | Lyophilized from a 0.22 μm filtered solution of 100 mM Tris-HCl, 10 mM Sodium citrate, 2 M NaCl, 6% Trehalose, pH 8.0. |
| Species | Human |
| Source | E. coli |
| Accession | Q00059 (S43-C246) |
| Gene ID | 7019 |
| Alternative Names | Transcription factor A, mitochondrial; mtTFA; Testis-specific high mobility group protein (TS-HMG); Hmgts |
| Tag | N-6*His |
| Endotoxin Level | <1 EU/μg, determined by LAL method. |
| Shipping Conditions | Room Temperature |
| Storage Information | Store at -20°C for up to 2 years from the date of receipt. After reconstitution, it's stable at 4°C for 1 week or -20°C for longer (with carrier protein). For extended storage, freeze in aliquots at -20°C or -80°C. |
Datasheet