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TFAM Protein, Mouse (His, Myc) is critical for regulating mitochondrial transcription, binding to light chain promoters, and essential for basal mtDNA transcription. In the TFB2M/POLRMT initiation complex, this recombinant mouse TFAM, expressed in E. coli with N-10*His and C-Myc tags, recruits POLRMT and promotes promoter opening.
Purity | Greater than 90 % as determined by reducing SDS-PAGE. |
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Molecular Weight | 34 kDa |
Appearance | Lyophilized Powder |
Formulation | Lyophilized from a 0.22 μm filtered solution of 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0. |
Species | Mouse |
Source | E. coli |
Accession | P40630 (S43-H243) |
Gene ID | 21780 |
Alternative Names | Transcription factor A, mitochondrial; mtTFA; Testis-specific high mobility group protein (TS-HMG); Hmgts |
Tag | N-10*His; C-Myc |
Endotoxin Level | <1 EU/μg, determined by LAL method. |
Shipping Conditions | Room Temperature |
Storage Information | Store at -20°C for up to 2 years from the date of receipt. After reconstitution, it's stable at 4°C for 1 week or -20°C for longer (with carrier protein). For extended storage, freeze in aliquots at -20°C or -80°C. |