TP4 (Nile tilapia piscidin) is an orally active, piscidin-like antimicrobial peptide. It inhibits various Gram-positive and negative strains (MIC: 0.03-10 μg/mL), exhibits hemolytic activity, and enhances immune response, antioxidant activity, and intestinal health against bacterial infections. TP4 also has anti-tumor effects, inducing necrosis via mitochondrial dysfunction in cancer cells.
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