TRAP1 Protein, Human (GST), an ATPase chaperone, plays a crucial role in protecting mitochondrial function and polarization, particularly downstream of PINK1 and mitochondrial complex I. This recombinant human TRAP1, expressed in E. coli with an N-GST tag, negatively regulates mitochondrial respiration, balancing oxidative phosphorylation and aerobic glycolysis.
| Purity | Greater than 90% as determined by reducing SDS-PAGE. |
|---|---|
| Molecular Weight | 54.5 kDa |
| Appearance | Lyophilized Powder |
| Formulation | Lyophilized after extensive dialysis against solution in PBS, 6% Trehalose, pH 7.4. |
| Species | Human |
| Source | E. coli |
| Accession | Q12931 (60S-308E) |
| Gene ID | 10131 |
| Alternative Names | Heat shock protein 75kDa; Heat shock protein 75kDa, mitochondrial; HSP 75; HSP75; HSP90L; mitochondrial; TNF receptor associated protein 1; TNFR-associated protein 1; TRAP-1; Trap1; TRAP1_HUMAN; Tumor necrosis factor type 1 receptor-associated protein |
| Tag | N-GST |
| Endotoxin Level | <1 EU/μg, determined by LAL method. |
| Shipping Conditions | Room Temperature |
| Storage Information | Store at -20°C for up to 2 years from the date of receipt. After reconstitution, it's stable at 4°C for 1 week or -20°C for longer (with carrier protein). For extended storage, freeze in aliquots at -20°C or -80°C. |
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