TTFA inhibits mitochondrial respiration by blocking respiratory chain complex II, binding to the ubiquinone sites Qp and Qd. This inhibition delays cell cycle progression and induces oxidative stress.
| Formal Name | 4, 4, 4-Trifluoro-1-(2-thienyl)-1, 3-butanedione |
|---|---|
| Purity | >98% |
| CAS Number | 326-91-0 |
| Formula | C8H5F3O2S |
| Molecular Weight | 222.18 |
| Appearance | Powder |
| Solubility | Dissolves in DMSO (up to 25 mg/mL) or in ethanol (up to 25 mg/mL) |
| Stability | ≥ 1 year |
| Application Procedures | First, dissolve in DMSO (up to 25 mg/mL) or in Ethanol (up to 25 mg/mL), and then dilute it into an aqueous buffer. Solutions in DMSO or Ethanol can be stored at -20°C for up to 1 month. |
| Storage Information | -20°C |
Mitochondrial Complex II inhibitor
Datasheet