This potent mitochondrial pyruvate carrier (MPC) inhibitor rapidly increases glucose uptake in human monocytes. It attenuates mitochondrial oxidative phosphorylation and increases glycolysis.
| Formal Name | 2-Cyano-3-(1-phenyl-1H-indol-3-yl)-2-propenoic acid |
|---|---|
| Purity | >98% |
| CAS Number | 56396-35-1 |
| Formula | C18H12N2O2 |
| Molecular Weight | 288.3 |
| Appearance | Powder |
| Solubility | Dissolves in DMSO (up to 30 mg/mL) or in ethanol (up to 8 mg/mL) |
| Stability | ≥ 1 year |
| Application Procedures | First, dissolve in DMSO (up to 30 mg/mL) or in Ethanol (up to 8 mg/mL), and then dilute it into an aqueous buffer. Solutions in DMSO or ethanol can be stored at -20°C for up to 1 month. |
| Storage Information | -20°C |
Mitochondrial pyruvate carrier inhibitor; cell impermeable
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