Zeaxanthin dipalmitate (Physalien), a wolfberry-derived carotenoid, offers anti-inflammatory and anti-oxidative stress effects. It interacts directly with p2X7 (Kd=81.2 nM) and AdipoR1 (Kd=533 nM) receptors in a dose-dependent manner. It restores mitochondrial autophagy impaired by ethanol intoxication. Useful for AFLD and RP research.
| Synonyms | Physalien |
|---|---|
| Purity | 0.95 |
| Formula | C72H116O4 |
| Molecular Weight | 1045.69 |
| SMILES | CC1(C)C(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C2=C(C)C[C@@H](OC(CCCCCCCCCCCCCCC)=O)CC2(C)C)=C(C)C[C@@H](OC(CCCCCCCCCCCCCCC)=O)C1 |
| Appearance | Solid |
| Color | Brown to reddish brown |
| Biological Target | Adiponectin Receptor; P2X Receptor; Autophagy |
| Target | p2X7/AdipoR1 receptor |
| Initial Source | Plants; Solanaceae; Lycium chinense Miller |
| Solubility | Ethanol: 1 mg/mL (0.96 mM, need ultrasonic and warming) |
| Shipping Conditions | Room Temperature |
| Storage Information | Powder: -80°C, 2 years; -20°C, 1 years. In solvent: -80°C, 6 months; -20°C, 1 month |
Datasheet