Online Inquiry
L-Glutamine
Cat. No. IC23040
CAS. No. 56-85-9
Key Features and Details
Category
Inhibitor&Activator
Purity
≥98.0%
Formula
C5H10N2O3
Product Details
Product Name
L-Glutamine
CAS No.
56-85-9
Molecular Weight
146.14
Synonyms
L-Glutamic acid 5-amide
Formula
C5H10N2O3
Appearance
Solid
Purity
≥98.0%
SMILES
N[C@@H](CCC(N)=O)C(O)=O
Product Overview
Description
L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells.
In Vitro Activity
L-Glutamine is important as a precursor for peptide and protein synthesis, amino sugar synthesis, purine and pyrimidine and thus nucleic acid and nucleotide synthesis, and also provides a source of carbons for oxidation in some cells. L-Glutamine is the most abundant extracellular amino acid in vivo (0.7 mM compared to an approximate L-glutamate concentration of 20 µM).
In BRIN-BD11 cells, culture for 24 h with 10 mM L-Glutamine compared with 1 mM resulted in substantial changes in gene expression with 148 genes upregulated more than 1.8-fold, and 18 downregulated more than 1.8-fold, including many genes involved in cellular signaling, metabolism, gene regulation, and the insulin-secretory response. L-Glutamine increases the activity of the Ca2+ regulated phosphatase calcineurin and the transcription factor Pdx1.
Storage & Handling
Storage
Powder, -20 °C, 3 years; 4 °C, 2 years
In solvent: -80 °C, 6 months, -20 °C, 1 month.
Shipping
Room temperature in continental US; may vary elsewhere.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
Related Products