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Cancer Biomarkers

Cancer biomarkers are biological indicators that reflect the presence and state of cancer in the body. They can be found in tissues, blood, and other body fluids and are widely used for the detection, diagnosis, and monitoring of various types of cancer. These molecular signatures play a pivotal role in personalized medicine, enabling targeted therapies and improved outcomes. At Protheragen, we specialize in the development and provision of advanced cancer biomarker related products that cater to the evolving needs of oncology research and clinical practice.

Types of Cancer Biomarkers

Imaging-based Biomarkers

Advanced imaging techniques such as CT, MRI, PET, and SPECT scans can detect the presence and location of tumors, providing critical information for diagnosis and treatment planning.

Blood-based Biomarkers

Proteins, circulating tumor cells, cell-free DNA, and other blood-borne molecules can serve as non-invasive indicators of cancer, enabling early detection and monitoring disease progression.

Tissue-based Biomarkers

Analyses of tumor biopsy samples through techniques like immunohistochemistry (IHC) can reveal molecular and cellular changes associated with specific cancer types and subtypes.

Genetic/Genomic Biomarkers

Cutting-edge genomic profiling methods, including DNA sequencing, RNA sequencing, and spatial transcriptomics, can uncover genetic and epigenetic alterations that drive cancer development and progression.

Our Cancer Biomarkers Related Products

A-B
aFGF/FGF1 Alpha-fetoprotein/AFP Angiopoietin-2/ANG2
AGR2 Angiopoietin 1 / ANG1 / ANGPT1 Angiotensin Converting Enzyme 1
APC/Adenomatous polyposis coli protein BCL2/Bcl-2 beta-Catenin/CTNNB1
Aurora A/AURKA BDNF/ANON2 bFGF/FGF2
BMI1    
C
c-Abl / ABL1 C4.4A/LYPD3 Cathepsin D/CTSD
c-Met/Met/HGFR Carbonic Anhydrase IX/CA9 CCL16 / HCC-4 / NCC4
CCR7 CD146/MCAM CEACAM7
CD109 CD147/EMMPRIN/Basigin CEACAM8/CD66b/CD67
CD171/L1CAM CD96/TACTILE CEACAM‑1/CD66a
CD208/DC-LAMP CD98/SLC3A2/4F2HC CGA/HCG
CD24 CDC73/HRPT2 CHI3L1/YKL40
CD31/PECAM-1 CDH13 / Cadherin-13 / H Cadherin CXCL17
CD38/ADPRC1 CDKN2D/p19ink4d CXCR4
CD44 CEACAM5/CEA/CD66e cyclin D1
CD74 CEACAM6/CD66c  
D-F
DEFA1 DNMT1 ECM1
DMBT1/Muclin E-Cadherin/CDH1/E-cad/CD324 EEBB3/HER3
EGFR/HER1 ENO2 Epidermal Growth Factor/EGF
Endoglin/CD105 EpCAM/TROP-1/TACSTD1 Epiregulin/EREG
ErbB4/HER4 Fibroblast Activation Protein alpha/FAP FOLR2
FGFR3/CD333 Folate Binding Protein/FOLR1  
G-H
GADD45A/DDIT1 Glypican 1/GPC1 GPA33
Galectin-3BP/LGALS3BP Glypican 3/GPC3/OCI-5 GPNMB/Osteoactivin
HE4/WFDC2/WAP5 HPGD/15-PGDH HSPA5
HER2/ErbB2    
I
ICAM-1/CD54 IGF1R/CD221/IGF-I R IL1B/IL-1B/IL-1 beta
IFNAR1 IGFBP-2 / IGFBP2 IL6/IL-6/Interleukin-6
IFNAR2/IFNABR IGFBP1/IGFBP-1 IL6R/IL-6R/CD126
IGBF/PRSP IGFBP3/IGFBP-3 IL6ST/gp130/CD130
IGF-2/IGF-II IL1A/IL-1A/IL-1F1 ING1
K-L
Kallikrein 10/KLK10 KIT / c-KIT / CD117 KLK5/Kallikrein 5
Kallikrein 2/KLK2 KLK3 KLK6/Kallikrein 6/Neurosin
KRT18/Cytokeratin18 LGALS3 LRRN3
Leptin LKB1  
M-N
M-CSF/CSF-1 MAPK3 MCP-1/CCL2
MAP2 Matriptase/ST14 MIF
MMP-3 MMP9/MMP-9/CLG4B MUC1/Mucin 1/CD227
MMP2/MMP-2/CLG4A MTDH/lyric/metadherin MYC associated factor X
NEK2 NGF/NGFB/beta-NGF NGL-1/LRRC4C
NELL2    
O-P
OLFM4/Olfactomedin-4 OTUB1 p21/WAF1/CDKN1A
OPN/Osteopontin OTUB2 p27/Kip1/CDKN1B
p53 PAI-1 / SerpinE1 PDCD4
p63 / TP63 PCNA PDGFRB/CD140b
PLAUR/CD87 PRL/Prolactin Prostatic Acid Phosphatase/ACPP
PON1 PRMT1/HRMT1L2 PSMA/FOLH1/GCPII
PTEN PTK6/Brk PTH1R/PTHR1
R-S
RB1/OSRC S100A7 S100A9/MRP-14
REG4 S100A8/MRP-8 S100B
RET S100A4 S100P
S100A1 S100A6 SERPINB3 / SCCA-1
S100A11 / S100C Survivin/BIRC5/API4 SOCS6
S100A15/S100A7A Syndecan-1/CD138/SDC1 SRC/Proto-oncogene c-Src
S100A16 S100A2 STYK1/NOK
T-X
TCL1A TGF-beta 1/TGFB1 TGF-beta 3/TGFB3
TEM7/PLXDC1 TGF-beta 2 TGFA / TGF-alpha
TGFBR1 / ALK-5 Tie2/CD202b/TEK TIMP-2/TIMP2
TGFBR3 / Betaglycan TIMP-1/TIMP1 TIMP-3/TIMP3
TIMP-4/TIMP4 TMEFF2 TOPBP1
TLE1 TNF-alpha/TNFA/TNFSF2 Urokinase/PLAU
VCAM1/VCAM-1/CD106 VEGFR2/KDR/Flk-1/CD309 XBP1
VEGF/VEGFA/VEGF165 VSIG1 More

Our team of seasoned biological experts will work closely with you to understand your unique challenges, goals, and constraints, and then leverage our extensive expertise and technological capabilities to develop a tailored solution that meets your exact needs. If you are interested in our products, please feel free to contact us for more information.

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.