AIFM2 Antibody (AA110-373)
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AIFM2 Antibody (AA110-373)

Cat. No. IA240211
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Product Details

Product Name
AIFM2 Antibody (AA110-373)
Description
Rabbit polyclonal antibody to AIFM2.
Species/Host
Rabbit
Isotype
IgG
Clonality
Polyclonal
Conjugation
Unconjugated
Immunogen
Recombinant Human Apoptosis-inducing factor 2 protein (110-373AA).
Reactivity
Human

Usage

Applications
ELISA, IF, IHC, WB
Dilution Range
WB: 1: 500-2000, IHC-P: 1: 20-200, IF: 1: 50-200
Note
For research use only

Target Information

Target
AIFM2
Gene Name
apoptosis inducing factor mitochondria associated 2
Gene Abbr.
AIFM2
Gene ID
84883
UniProt ID
Q9BRQ8
Molecular Weight
41 kDa
Alternative Names
Anti-Apoptosis-inducing factor 2 (EC 1.-.-.-)
Cellular Localization
Cell membrane and Cytoplasm.
Function
A NAD(P)H-dependent oxidoreductase that acts as a key inhibitor of ferroptosis (PubMed:31634899, PubMed:31634900, PubMed:35922516). At the plasma membrane, catalyzes reduction of coenzyme Q/ubiquinone-10 to ubiquinol-10, a lipophilic radical-trapping antioxidant that prevents lipid oxidative damage and consequently ferroptosis (PubMed:31634899, PubMed:31634900).
Sequence Similarities
Belongs to the FAD-dependent oxidoreductase family.

Storage & Handling

Storage
Store at -20°C. Avoid freeze/thaw cycles.
Storage Buffer
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol
Shipping
Shipped at 4°C
Form/Appearance
Liquid
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
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