Iron Supplement Development Service
Iron is an essential micronutrient critical for oxygen transport, cellular respiration, and DNA synthesis. Its deficiency can give rise to various conditions such as anemia, fatigue, and impaired intellect. Iron deficiency is thought to be the most prevalent form of micronutrient deficiency across the world. Protheragen is the top iron metabolism research service provider and offers our expertise to develop iron supplement development solutions that address this prevalent health issue. Our iron supplement development services are created to help nutraceutical companies, scientists, and entrepreneurs commercialize iron-containing health products with proven efficacy and safety.
Introduction to Iron Supplements
Iron supplements address nutritional gaps by providing iron in a supplement form for individuals suffering from an iron deficiency or from a condition where natural dietary absorption is insufficient. They are a type of nutraceutical and come in several formulations and concentrations, designed to prevent or correct iron deficiency without the strict regulatory oversight associated with prescription medications.
Fig.1 Range of organ involvement in Joubert syndrome and classification in clinical subgroups (in bold). (Romani M, et al., 2013)
Categories of Iron Supplements
The types of iron supplements can be grouped based on their method of delivery and composition. Knowing these classes is vital for designing nutraceutical products that would ideally achieve the intended goals.
| Categories | Description |
| Ferrous Salts | These are among the most prevalent forms of iron, which are also readily absorbed by the body, including ferrous sulfate, ferrous gluconate, etc. |
| Polysaccharide-Iron Complex (PIC) | A form of chelated iron that is associated with fewer incidences of gastrointestinal distress than ferrous salts. |
| Carbonyl Iron | A highly pure form of elemental iron for enhanced absorption to help you restore and increase ferritin levels. |
| Heme Iron Polypeptide (HIP) | This type is sourced from animal sources, is easy to absorb by the body, and is well tolerated. |
| Liposomal Iron | Iron is enclosed with the goal of enhancing absorption and minimizing GI side effects. |
| Plant-Based Iron | Derived from plant sources, often combined with other nutrients to enhance absorption. |
| Ferric Salts | Less frequently found in supplements, due to lower bioavailability, but there are some forms, such as ferric pyrophosphate, which is commonly used in food fortification because it's so stable. |
Our Services
As a leading iron metabolism-related nutraceuticals development services supplier, Protheragen focuses on all kinds of iron supplements, researching and developing in the industry. We assist from early concept and planning through preclinical testing and regulatory consultation to ensure your product is effective, safe, and in compliance. Our technical expertise follows the latest scientific advances, bioavailability studies, and consumer trends to assist you in developing cutting-edge products at the forefront of the market.
Development of Custom Formulation
Create a formulation of an iron supplement for a specific market, meeting the needs of the target population, dosage preferences, and desired form (capsule, tablet, liquid, or gummy).
Nutraceutical Safety
Testing Service
Assessment of safety for your iron supplement by thorough examination for contaminants, heavy metals, and allergens, ensuring safety.
Bioavailability Enhancement Strategies
Utilizing specific cofactors to promote iron absorption, and other methods to enhance its absorption as well as its relative bioavailability.
Nutraceutical Efficacy Testing Service
Claim verification of the biological activity and health benefits of your iron supplement, including in vitro and in vivo testing.
Nutraceutical Stability Testing Service
Evaluating the potency and stability of the iron supplement over time and under different conditions to determine shelf life.
Dissolution Testing
Service
Measure of the rate and extent to which iron is released from the supplement under simulated biological conditions.
Types of Iron Supplement Development
- Supplement for Ferrous Iron
- Supplement for Ferric Iron
- Polysaccharide-Iron Complex (PIC) Supplement
- Supplement for Carbonyl Iron
- Heme Iron Polypeptide (HIP) Supplement
- Liposomal Iron Supplement
- Supplement for Plant-Based Iron
- And More
Workflow of Iron Supplement Development Services
By working with Protheragen, you benefit from a high-caliber nutraceutical development team that includes a dedicated team for iron metabolism and nutraceuticals, as well as being bound by a commitment to scientific rigor. We can help you develop novel and effective iron supplements with true impact on global health, thanks to our extensive knowledge and state-of-the-art technology. Should you be interested, please reach out.
Reference
- Travali, E et al. "Efficacy and safety of a food supplement for iron deficiency anaemia: A monocentric prospective study." Current research in food science 7 (2023): 100637.