Nutraceutical Safety Testing Service
In this area of research on iron metabolism, the discovery and development of safe and effective nutraceuticals are very important. Safety testing of nutraceuticals is an important step to ensure that these products are devoid of toxic contaminants, do not cause side effects, and are safe for human consumption. Protheragen offers professional iron metabolism-related nutraceutical development services, especially focusing on the safety testing of nutraceuticals. That takes intense scientific examination, looking for any possible risk, evaluating ingredient quality, and testing for product safety.
Overview of Nutraceutical Safety Testing
Nutraceuticals, dietary supplements that provide beneficial effects, are being increasingly used, in particular in the management of disorders due to iron metabolism. The main objective of testing for the safety of nutraceuticals is to ensure that consumers a product is safe when used as the manufacturer intended. This covers an extensive range of analyses, ranging from impurity identification and toxicity assessment to long-term stability.
Fig.1 Nutraceutical and functional food safety analysis. (Ali, D.S., et al., 2025)
Recent development of analytical methodologies, including those using high-resolution instrumentation such as mass spectrometry (MS) alongside advancing chromatography tools, has significantly enhanced the capacity to detect contaminants at trace levels and quantify active substances. Moreover, in vitro models such as cell-based assays and organ-on-a-chip technology provide more rapid and ethical alternatives to traditional animal tests for initial safety screening.
Classification of Nutraceutical Safety Testing
Safety assessment of nutraceuticals utilizes a wide range of methods, which include in vitro, in vivo, and analytical studies.
Chemical Analysis
Detecting and quantifying heavy metals, pesticides, microbial contaminants, and other impurities. This also includes the discovery and quantification of the actives.
Toxicology Studies
Testing the toxicity of the nutraceutical using different models. This may include acute and sub-chronic toxicity tests, as well as genotoxicity and reproductive toxicity studies.
Our Services
Protheragen, supported by advanced nutraceutical safety testing platforms, offers dedicated testing solutions for products associated with iron metabolism. Drawing on cutting-edge technology and a team of skilled scientists, we provide accurate, compliant results that speed up your product from development to market.
Nutraceutical Types for Safety Testing
Types of Nutraceutical Safety Testing Services
| Types | Purpose | Methods |
| Microbial Testing | To identify and measure potentially dangerous microorganisms, including bacteria, yeasts, and molds. | Total Aerobic Plate Count Yeast & Mold Counts Pathogen-Specific Assays |
| Heavy Metal Testing | Detection and measurement of concentrations of lead, arsenic, cadmium, mercury, and other heavy metals harmful to health. | Inductively Coupled Plasma Mass Spectrometry |
| Pesticide Residue Testing | Identification and quantification of different pesticide residues that may accumulate in the raw materials. | Gas Chromatography-Mass Spectrometry Liquid Chromatography-Mass Spectrometry |
| Mycotoxin Screening | To identify and measure specific mycotoxins mitigating product risk, which are toxic metabolites produced by specific molds. | Enzyme-Linked Immunosorbent Assay High-Performance Liquid Chromatography Liquid Chromatography-Mass Spectrometry |
Nutraceutical Toxicity Research Services
- Abuse and Dependence Liability Testing
- Genetic Toxicology
- Ototoxicity Testing
- Phototoxicity Testing
- Skin Irritation, Corrosion, and Sensitization
- General Toxicology
- Neurotoxicology
- Ocular Toxicology
- Infusion Toxicology
- Inhalation Toxicology
- Developmental and Reproductive Toxicology
- Others
Collaborate with Protheragen and ensure the safety and success of your iron metabolism-related nutraceutical development project for innovative and safer health solutions. Please do not hesitate to contact us if you are interested in our services.
Reference
- Ali, Diyar Salahuddin, et al., "Nutraceutical and functional foods: developmental of toxicity testing and safety assessment." Euro-Mediterranean Journal for Environmental Integration (2025).