Sun Care Products Development Service
The metabolism is potently implicated in ultraviolet-induced skin damage. A superfluity of iron enhances ROS production through the Fenton reaction, promoting photoaging, hyperpigmentation, and DNA damage. As the leading service provider of integrated research services in iron metabolism disorder, Protheragen utilizes the extensive knowledge in iron biology to support the cosmetic market with cutting-edge solutions for developing advanced sun care products.
Introduction to Iron Metabolism and Photoprotection
With rising global demand for advanced photoprotection, iron-targeted sun protection is a revolutionary frontier. Impaired iron homeostasis has been associated with oxidative stress, a major factor in skin aging and in damage caused by ultraviolet radiation.
Fig.1 Iron chelator protects mitochondrial membranes from UVA photodamage. (Reelfs, O., et al., 2016)
Ultraviolet radiation releases free iron from cellular proteins, which catalyzes ROS generation via Fenton reactions, accelerating skin barrier dysfunction and photoaging. By regulating the iron metabolism process, sun care products can provide a unique approach to improved photoprotection, not simply by battling against the factors of ultraviolet rays, but also by addressing the underlying cause of sun-induced damage.
Effects of Iron Metabolism-related Sun Care Products
These groundbreaking sun care products containing iron metabolism-related substances are formulated to affect the following aspects.
Regulate Iron Levels
Ingredients that chelate excess iron or iron transporter modulator ingredients could help regulate the healthy iron level in the skin.
Reduce Oxidative Stress
By controlling iron-mediated ROS generation, these products can significantly enhance the skin's antioxidant defense.
Mitigate Inflammation
Regulating iron levels can reduce the inflammatory processes that result from UV exposure.
Improve Overall Skin Health
A balanced iron metabolism promotes better skin barrier function, more efficient repair mechanisms, and a healthier overall complexion.
Our Services
Based on our solid know-how in iron metabolism research, we provide one-stop services, ranging from proof of concept and development of novel sun care products. Our sun care products development services targeted iron chelation and metabolic pathway modulation to eliminate oxidative stress at its root cause. Unlike traditional sunscreens that only block UV rays, our defense designs provide physical UV barrier protection and molecular iron regulation to provide the most complete skin defense.
Types of Iron Metabolism-related Sun Care Products Development
| Types | Description |
| Sunscreens With Antioxidants | Formulations integrating conventional UV filters with iron chelators or components that promote iron homeostasis for enhanced protection against oxidative damage. |
| After-Sun Products | Products intended to soothe, restore, and rejuvenate skin after sun exposure focused on iron-mediated oxidative stress and inflammation. |
| Anti-Aging Sunscreens | Sunscreens and daily care products that provide protection against ultraviolet radiation and also address an iron-mediated cascade mechanism of photoaging associated with collagen degradation and wrinkle formation. |
| Sunscreen for Pigmentation | Formulations designed to reduce and prevent sun-induced hyperpigmentation by influencing iron-driven processes in melanin synthesis. |
| Moisturizers with SPF | Products incorporating iron metabolism-modulating components for sustained photoprotection and reinforce skin barrier integrity. |
Sun Care Products Development Services
Boost sun care innovation with Protheragen's science-based development support. Get in touch with our experts today for a custom solution and bring your breakthrough cosmetics in photoprotection to market. Find out more about how our expertise in iron metabolism can enhance your sun care product range and help you stand out in the competitive cosmetic market.
References
- Pourzand, Charareh et al. "Shedding a New Light on Skin Aging, Iron- and Redox-Homeostasis and Emerging Natural Antioxidants." Antioxidants (Basel, Switzerland) 11.3 (2022): 471.
- Reelfs, Olivier et al. "A Powerful Mitochondria-Targeted Iron Chelator Affords High Photoprotection against Solar Ultraviolet A Radiation." The Journal of Investigative Dermatology 136.8 (2016): 1692-1700.