Iron Absorption Enhancers Development Service
Iron deficiency is a common health issue, and while iron supplementation is ample, the bioavailability of iron is indeed quite a challenge. Protheragen, a leader in iron metabolism research services, leverages deep scientific expertise to offer specialized iron absorption enhancers development tailored for the nutraceutical and functional food industry. We aim to develop safe, effective, and scientifically validated solutions to optimize iron bioavailability.
Introduction to Iron Absorption Enhancers
Numerous factors, such as the type of iron, compounds that inhibit absorption like phytates and tannins, and even compounds that assist absorption, can all play a part in iron absorption. Iron absorption enhancers are defined as either methods or compounds that increase the absorption of food or an iron supplement. As distinct from pharmaceuticals, nutraceuticals have an emphasis on health benefits, seeking to manage or avert health problems through nutritional support. About iron, this means designing ingredients or formulations that help improve the body's natural mechanisms for absorbing iron.
Fig.1 Key promoters and antagonists of iron bioavailability. (Piskin, E., et al., 2022)
Classification of Iron Absorption Enhancers
Enhancers of iron absorption may be classified according to their mechanisms or chemical composition.
| Categories | Description |
| Chelators/Ligands | Some molecules, such as amino acids or organic acids, bind to iron, forming soluble complexes that facilitate absorption. |
| Reducing Agents | The compounds that convert iron from Fe3+ to Fe2+ are generally more bioavailable. Here is an example of one of those, and that is Vitamin C (ascorbic acid). |
| Prebiotics/Probiotics | Some gut microbiota might interfere with iron absorption, particularly pre/probiotics, which could promote its absorption, although indirectly. |
| Peptides/Proteins | Particular protein fragments originating from selected types of food can have iron-binding or iron-absorption-increasing potential. |
| Natural Extracts/Phytochemicals | Plant-derived compounds that indirectly diminish absorption inhibitors or directly enhance iron absorption. |
Our Services
Leveraging our extensive knowledge of iron metabolism, we offer a complete range of services to accelerate the development of nutraceutical iron absorption enhancers. Also, we offer full-service development support with biological efficacy integrated with scientific rigor and compliance with all relevant regulations. Helping you develop targeted, effective, and iron deficiency-specific nutraceutical products is our goal.
Iron Absorption Enhancers Development Services
We offer a full spectrum of development services for iron absorption enhancers in nutraceuticals.
Nutraceutical Formulation Development
Developing and optimizing iron-enhancer formulations involving ingredient selection, dosage form development, flavor masking, and optimization of processing steps.
Nutraceutical Safety Testing Service
Performing product safety assessment and regulatory compliance, including toxicology, allergen testing, and extensive contaminant analysis.
Nutraceutical Efficacy Testing
Assessing functional benefits of enhanced absorption iron nutraceuticals on iron bioavailability using appropriate preclinical models.
Nutraceutical Bioavailability Studies
Designing and conducting bioavailability studies to evaluate the absorption of iron using in vitro and animal models.
Nutraceutical Stability Testing
Conducting comprehensive accelerated and real-time stability studies under different environmental conditions to evaluate enhancer stability.
Workflow of Iron Absorption Enhancers Development Services
Why Choose Us?
- Specialized Expertise: Utilize extensive scientific knowledge of iron metabolism and its complex regulators to enhance iron absorption strategies.
- Integrated Services: Providing seamless, comprehensive support for nutraceutical development. This holistic approach simplifies your project process from start to finish.
- Cutting-Edge Technologies: By taking state-of-the-art in vitro and in vivo models to potentiate efficacious and safe evaluation, ensure accelerated development for your iron absorption enhancers.
- Bespoke Solutions: Providing bespoke services that accommodate your product development needs and timelines. Each project is presented with an exclusive solution.
Collaborate with Protheragen to get the most value out of your iron-based nutraceuticals. Our comprehensive services and capabilities can help you get your iron-fortified nutraceuticals to market faster. Please contact us to find out how our iron absorption enhancers development services can help you succeed.
Reference
- Piskin, Elif et al. "Iron Absorption: Factors, Limitations, and Improvement Methods." ACS omega 7.24 (2022): 20441-20456.