AIFM2 Antibody (AA121-180)
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AIFM2 Antibody (AA121-180)

Cat. No. IA240212
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Product Details

Product Name
AIFM2 Antibody (AA121-180)
Description
AMID antibody.
Species/Host
Rabbit
Isotype
IgG
Clonality
Polyclonal
Conjugation
Unconjugated
Immunogen
KLH conjugated synthetic peptide derived from human AMID/AIFM2 (121-180/373 aa).
Reactivity
Bovine, Human, Mouse, Porcine, Rat, Sheep

Usage

Applications
ELISA, IF, IHC-Fr, IHC-P
Dilution Range
IHC-P: 1/100-500, IHC-F: 1/100-500, IF: 1/100-500, ELISA: 1/5000-10000
Concentration
1 mg/mL
Note
For research use only

Target Information

Target
AIFM2
Gene Name
apoptosis inducing factor mitochondria associated 2
Gene Abbr.
AIFM2
Gene ID
84883
UniProt ID
Q9BRQ8
Molecular Weight
41 kDa
Alternative Names
aifm2, AIFM2_HUMAN, AMID
Cellular Localization
Cell membrane and Cytoplasm.
Function
A NAD(P)H-dependent oxidoreductase that acts as a key inhibitor of ferroptosis (PubMed:31634899, PubMed:31634900, PubMed:35922516). At the plasma membrane, catalyzes reduction of coenzyme Q/ubiquinone-10 to ubiquinol-10, a lipophilic radical-trapping antioxidant that prevents lipid oxidative damage and consequently ferroptosis (PubMed:31634899, PubMed:31634900).
Sequence Similarities
Belongs to the FAD-dependent oxidoreductase family.

Storage & Handling

Storage
Store at -20°C. Avoid freeze/thaw cycles.
Storage Buffer
0.01M TBS(pH7.4) with 1% rAlbumin, 0.03% Proclin 300 and 50% Glycerol.
Shipping
Shipped at 4°C
Form/Appearance
Liquid
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
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