AIFM2 Antibody (Middle Region)
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AIFM2 Antibody (Middle Region)

Cat. No. IA240222
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Product Details

Product Name
AIFM2 Antibody (Middle Region)
Description
Rabbit polyclonal antibody to AIFM2.
Species/Host
Rabbit
Isotype
IgG
Clonality
Polyclonal
Conjugation
Unconjugated
Immunogen
A peptide corresponding to middle region of human AIFM2 protein.
Reactivity
Mouse, Rat

Usage

Applications
ELISA, IHC, WB
Dilution Range
WB: 1/200-1000
Note
For research use only

Target Information

Target
AIFM2
Gene Name
apoptosis inducing factor mitochondria associated 2
Gene Abbr.
AIFM2
Gene ID
84883
UniProt ID
Q9BRQ8
Molecular Weight
41 kDa
Alternative Names
AMID, PRG3, RP11-367H5. 2, DKFZp686L1298, AIFM2
Cellular Localization
Cell membrane and Cytoplasm.
Function
A NAD(P)H-dependent oxidoreductase that acts as a key inhibitor of ferroptosis (PubMed:31634899, PubMed:31634900, PubMed:35922516). At the plasma membrane, catalyzes reduction of coenzyme Q/ubiquinone-10 to ubiquinol-10, a lipophilic radical-trapping antioxidant that prevents lipid oxidative damage and consequently ferroptosis (PubMed:31634899, PubMed:31634900).
Sequence Similarities
Belongs to the FAD-dependent oxidoreductase family.

Storage & Handling

Storage
Store at -20°C. Avoid freeze/thaw cycles.
Storage Buffer
Lyophilized powder with 1% rAlbumin and 0.02% NaN3.
Shipping
Shipped at 4°C
Form/Appearance
Lyophilized
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
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