Chicken Glutathione Peroxidase 4 (GPX4) ELISA Kit
Online Inquiry

Chicken Glutathione Peroxidase 4 (GPX4) ELISA Kit

Cat. No. IK240240
Product Size    

Product Details

Product Name
Chicken Glutathione Peroxidase 4 (GPX4) ELISA Kit
Product Alternative Names
MCSP; PHGPx; SnGPx; SnPHGPx; Phospholipid Hydroperoxidase; Phospholipid hydroperoxide glutathione peroxidase; mitochondrial
Reactivity
Chicken
Sensitivity
7.2 pg/mL
Detection Range
31.25-2000 pg/mL
Assay Type
Sandwich
Description
The kit is designed to analyse the presence of the target Glutathione Peroxidase 4 (GPX4) in Chicken biological samples using enzyme-linked immunosorbent assay technology.
Sample Type
Serum, Plasma, Tissue Homogenates, Cell Lysates, Cell Culture Supernates and Other Biological Fluids.
Notes
For research use only.
Applications
ELISA

Usage

Detection Method
Colorimetric
Platform
Microplate reader

Target Information

Gene Symbol
GPX4
Related Gene ID
Gene Name
glutathione peroxidase 4
Alias Symbols
GPx-4; PHGPx; snGPx; GSHPx-4; mtPHGPx
Protein Name
Phospholipid hydroperoxide glutathione peroxidase
Related Uniprot ID
Molecular Weight
~22 kDa
Sequence Similarities
Belongs to the glutathione peroxidase family.
Tissue Specificity
Present primarily in testis.
Cellular Localization
Cytoplasm and Mitochondrion.
Function
Required to prevent cells from ferroptosis, a non-apoptotic cell death resulting from an iron-dependent accumulation of lipid reactive oxygen species (PubMed:24439385). The presence of selenocysteine (Sec) versus Cys at the active site is essential for life: it provides resistance to overoxidation and prevents cells against ferroptosis (By similarity).
Disease Area
Spondylometaphyseal dysplasia, Sedaghatian type (SMDS)

Storage & Handling

Storage
Store at 2-8 °C. Avoid repeated freeze-thaw cycles.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
Related Products