FACL4/ACSL4 Antibody (AA250-300)
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FACL4/ACSL4 Antibody (AA250-300)

Cat. No. IA240178
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Product Details

Product Name
FACL4/ACSL4 Antibody (AA250-300)
Description
ACSL4/FACL4 Antibody.
Species/Host
Rabbit
Isotype
IgG
Clonality
Polyclonal
Conjugation
Unconjugated
Immunogen
Between 250 and 300.
Reactivity
Human

Usage

Applications
IP, WB
Dilution Range
WB: 1/2000-10000, IP: 2-10 µg/mg lysate
Concentration
1000 µg/mL
Note
For research use only

Target Information

Target
ACSL4/FACL4
Gene Name
acyl-CoA synthetase long chain family member 4
Gene Abbr.
ACSL4/FACL4
Gene ID
2182
UniProt ID
O60488
Molecular Weight
79 kDa
Alternative Names
fatty-acid-Coenzyme A ligase, long-chain 4
Cellular Localization
Cell membrane and Endoplasmic reticulum.
Function
Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoA for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:24269233, PubMed:22633490, PubMed:21242590). Preferentially activates arachidonate and eicosapentaenoate as substrates (PubMed:21242590). Modulates prostaglandin E2 secretion (PubMed:21242590).
Disease Area
Intellectual developmental disorder, X-linked 63 (XLID63), AMME complex (ATS-MR)
Sequence Similarities
Belongs to the ATP-dependent AMP-binding enzyme family.

Storage & Handling

Storage
Store at 2-8°C. Avoid freeze/thaw cycles.
Storage Buffer
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Shipping
Shipped at 4°C
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
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