FACL4/ACSL4 Antibody (N-Terminus)
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FACL4/ACSL4 Antibody (N-Terminus)

Cat. No. IA240189
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Product Details

Product Name
FACL4/ACSL4 Antibody (N-Terminus)
Description
ACSL4 / FACL4 Antibody (N-Terminus).
Species/Host
Rabbit
Isotype
IgG
Clonality
Polyclonal
Conjugation
Unconjugated
Immunogen
Synthetic peptide from N-Terminus of human ACSL4 (O60488, NP_004449).
Reactivity
Human

Usage

Applications
IHC, IHC-P, WB
Dilution Range
IHC/IHC-P: 5 µg/ml, WB: 0.2 - 1 µg/ml
Concentration
0.5 mg/mL
Note
For research use only

Target Information

Target
ACSL4 / FACL4
Gene Name
acyl-CoA synthetase long chain family member 4
Gene Abbr.
ACSL4 / FACL4
Gene ID
2182
UniProt ID
O60488
Molecular Weight
79 kDa
Alternative Names
ACSL4, Acyl-CoA synthetase 4, ACS4, FACL4, LACS4
Cellular Localization
Cell membrane and Endoplasmic reticulum.
Function
Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoA for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:24269233, PubMed:22633490, PubMed:21242590). Preferentially activates arachidonate and eicosapentaenoate as substrates (PubMed:21242590). Modulates prostaglandin E2 secretion (PubMed:21242590).
Disease Area
Intellectual developmental disorder, X-linked 63 (XLID63), AMME complex (ATS-MR)
Sequence Similarities
Belongs to the ATP-dependent AMP-binding enzyme family.

Storage & Handling

Storage
Store at -20°C. Avoid freeze/thaw cycles.
Storage Buffer
PBS, 0.09% sodium azide, 2% sucrose. PBS, 0.09% sodium azide, 2% sucrose.
Shipping
Shipped at 4°C
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
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