The product is designed for analyse the presence of the target Apoptosis-inducing factor 2 (AIFM2) in Monkey biological samples using enzyme-linked immunosorbent assay technology.
Sample Type
Serum, Plasma, Cell Culture Supernatants, Body Fluid and Tissue Homogenate.
Belongs to the FAD-dependent oxidoreductase family.
Tissue Specificity
Heart.
Cellular Localization
Cell membrane, Cytoplasm, Lipid droplet, Membrane, Mitochondrion and Nucleus.
Function
A NAD(P)H-dependent oxidoreductase that acts as a key inhibitor of ferroptosis (PubMed:31634899, PubMed:31634900, PubMed:35922516).
At the plasma membrane, catalyzes reduction of coenzyme Q/ubiquinone-10 to ubiquinol-10, a lipophilic radical-trapping antioxidant that prevents lipid oxidative damage and consequently ferroptosis (PubMed:31634899, PubMed:31634900).
Storage & Handling
Storage
Store at 2-8 °C. Avoid repeated freeze-thaw cycles.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.