Mouse FACL4/ACSL4 Monoclonal Antibody
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Mouse FACL4/ACSL4 Monoclonal Antibody

Cat. No. IA240188
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Product Details

Product Name
Mouse FACL4/ACSL4 Monoclonal Antibody
Description
FACL4/ACSL4 Antibody (monoclonal, 4I7).
Species/Host
Mouse
Isotype
IgG1
Clonality
Monoclonal
Conjugation
Unconjugated
Immunogen
A synthetic peptide corresponding to a sequence of human FACL4/ACSL4 (EPWTPETGLVTDAFKLKRKELR).
Reactivity
Human

Usage

Applications
FC, ICC, IF, IHC, WB
Dilution Range
WB: 0.25-0.5 μg/ml, IHC-P: 2-5 μg/ml, ICC/IF: 5 μg/ml, FC: 1-3 μg/1x106 cells
Concentration
500 µg/mL
Note
For research use only

Target Information

Target
ACSL4
Gene Name
acyl-CoA synthetase long chain family member 4
Gene Abbr.
ACSL4
Gene ID
2182
UniProt ID
O60488
Molecular Weight
79 kDa
Cellular Localization
Cell membrane and Endoplasmic reticulum.
Function
Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoA for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:24269233, PubMed:22633490, PubMed:21242590). Preferentially activates arachidonate and eicosapentaenoate as substrates (PubMed:21242590). Modulates prostaglandin E2 secretion (PubMed:21242590).
Disease Area
Intellectual developmental disorder, X-linked 63 (XLID63), AMME complex (ATS-MR)
Sequence Similarities
Belongs to the ATP-dependent AMP-binding enzyme family.

Storage & Handling

Storage
Store at -20°C. Avoid freeze/thaw cycles.
Shipping
Shipped at 4°C
Form/Appearance
Lyophilized
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
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