Rabbit FACL4/ACSL4 Monoclonal Antibody
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Rabbit FACL4/ACSL4 Monoclonal Antibody

Cat. No. IA240191
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Product Details

Product Name
Rabbit FACL4/ACSL4 Monoclonal Antibody
Description
ACSL4 Antibody.
Species/Host
Rabbit
Isotype
IgG
Clonality
Monoclonal
Conjugation
Unconjugated
Immunogen
A synthetic peptide of human FACL4.
Reactivity
Human, Mouse, Rat

Usage

Applications
IHC-P, IP, WB
Dilution Range
WB: 1/500-1/1000, IHC: 1/50-1/100, IP: 1/20
Concentration
0.3 mg/mL
Note
For research use only

Target Information

Target
ACSL4
Gene Name
acyl-CoA synthetase long chain family member 4
Gene Abbr.
ACSL4
Gene ID
2182
UniProt ID
O60488
Molecular Weight
79 kDa
Alternative Names
ACS4, FACL4, LACS4, MRX63, MRX68
Cellular Localization
Cell membrane and Endoplasmic reticulum.
Function
Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoA for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:24269233, PubMed:22633490, PubMed:21242590). Preferentially activates arachidonate and eicosapentaenoate as substrates (PubMed:21242590). Modulates prostaglandin E2 secretion (PubMed:21242590).
Disease Area
Intellectual developmental disorder, X-linked 63 (XLID63), AMME complex (ATS-MR)
Sequence Similarities
Belongs to the ATP-dependent AMP-binding enzyme family.

Storage & Handling

Storage
Store at -20°C. Avoid freeze/thaw cycles.
Storage Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% rAlbumin.
Shipping
Shipped at 4°C
Form/Appearance
Liquid
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
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