Ceruloplasmin is a blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe2+ to Fe3+ without releasing radical oxygen species. It is involved in iron transport across the cell membrane. Provides Cu2+ ions for the ascorbate-mediated deaminase degradation of the heparan sulfate chains of GPC1.
Disease Area
Aceruloplasminemia (ACERULOP).
Storage & Handling
Storage
Store at -20 °C. Avoid repeated freeze-thaw cycles.
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