Product Name
ADHFE1 HEK293T Cell Transient Overexpression Lysate
Alternate Names
ADH8, alcohol dehydrogenase, iron containing, 1, EC 1.1.99.24, Fe-containing alcohol dehydrogenase, HOTmitochondrial, MGC48605
Expression Host
HEK293T
Species
Human
Type
293T Cell Transient Overexpression
Gene
ADHFE1
Plasmid
pCMV-ADHFE1 full-length
Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Background
ADHFE1, also known as hydroxyacid-oxoacid transhydrogenase, contains a 50 kDa, 45 kDa, 33 kDa, and 27 kDa isoform, and is involved in oxidation in mammalian tissues. Current research on ADHFE1 includes its relation to a variety of disorders and diseases, including alcohol-related neurodevelopmental disorder, pneumonia, patellar tendinitis, hepatoblastoma, cholangiocarcinoma, Pontiac fever, alcoholism, Legionnaires' disease, and intrahepatic cholangiocarcinoma. This protein is linked to pyruvate metabolism, the citric acid (TCA) cycle, and respiratory electron transport, where it interacts with GNAQ and LIPC.