AIFM2 Antibody (AA205-233)
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AIFM2 Antibody (AA205-233)

Cat. No. IA240214
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Product Details

Product Name
AIFM2 Antibody (AA205-233)
Description
AIFM2 Antibody.
Species/Host
Rabbit
Isotype
IgG
Clonality
Polyclonal
Conjugation
Unconjugated
Immunogen
This AIFM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-233 amino acids from the Central region of human AIFM2.
Reactivity
Human

Usage

Applications
WB
Dilution Range
WB: 1/1000
Concentration
batch dependent
Note
For research use only

Target Information

Target
AIFM2
Gene Name
apoptosis inducing factor mitochondria associated 2
Gene Abbr.
AIFM2
Gene ID
84883
UniProt ID
Q9BRQ8
Molecular Weight
41 kDa
Alternative Names
Apoptosis-inducing factor 2, 1
Cellular Localization
Cell membrane and Cytoplasm.
Function
A NAD(P)H-dependent oxidoreductase that acts as a key inhibitor of ferroptosis (PubMed:31634899, PubMed:31634900, PubMed:35922516). At the plasma membrane, catalyzes reduction of coenzyme Q/ubiquinone-10 to ubiquinol-10, a lipophilic radical-trapping antioxidant that prevents lipid oxidative damage and consequently ferroptosis (PubMed:31634899, PubMed:31634900).
Sequence Similarities
Belongs to the FAD-dependent oxidoreductase family.

Storage & Handling

Storage
Store at -20°C. Avoid freeze/thaw cycles.
Storage Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Shipping
Shipped at 4°C
Form/Appearance
Liquid
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
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