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(+/-)-Epigallocatechin Gallate-13C3
Cat. No. IC23094
CAS. No.
Key Features and Details
Category
Inhibitor&Activator
Formula
C1913C3H14O11
Product Details
Product Name
(+/-)-Epigallocatechin Gallate-13C3
Molecular Weight
457.32
Formula
C1913C3H14O11
SMILES
O=C(O[13C@]1[13C@@](C2=CC(O)=C(O)C(O)=C2)OC3=CC(O)=CC(O)=C3[13C]1)C4=CC(O)=C(O)C(O)=C4
Product Overview
Description
(+/-)-Epigallocatechin Gallate-13C3 is the 13C-labeled (-)-Epigallocatechin Gallate. (-)-Epigallocatechin Gallate is a tea flavonoid with potent antioxidant, antiinflammatory, and anticarcinogenic properties. (-)-Epigallocatechin Gallate is reported to inhibit EGFR signaling and thereby exert anticancer effects. (-)-Epigallocatechin Gallate (EGCG) is a glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) inhibitor. Epigallocatechin-3-gallate induces oxidative phosphorylation (OXPHOS) by activating cytochrome c oxidase.
In Vitro Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Storage & Handling
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping
Room temperature in continental US; may vary elsewhere.
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