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FIN56
Cat. No. IC23131
CAS. No. 1083162-61-1
Key Features and Details
Category
Inhibitor&Activator
Purity
99.27%
Formula
C25H31N3O5S2
Product Details
Product Name
FIN56
CAS No.
1083162-61-1
Molecular Weight
517.66
Formula
C25H31N3O5S2
Appearance
Solid
Purity
99.27%
SMILES
O=S(C1=CC(/C2=N\O)=C(C3=C2C=C(S(=O)(NC4CCCCC4)=O)C=C3)C=C1)(NC5CCCCC5)=O
Product Overview
Description
FIN56 is a specific inducer of ferroptosis. FIN56 induces ferroptosis by inducing degradation of GPX4. FIN56 also binds to and activates squalene synthase.
In Vitro Activity
FIN56 (5 μM) can trigger ferroptosis by inhibition of glutathione peroxidase 4 (GPX4).
FIN56 (5 μM, 10 hours) depletes GPX4 protein in HT-1080 cells.
Storage & Handling
Storage
Powder, -20 °C, 3 years; 4 °C, 2 years
In solvent: -80 °C, 6 months, -20 °C, 1 month.
Shipping
Room temperature in continental US; may vary elsewhere.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
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