FINO2 is a potent ferroptosis inducer. FINO2 inhibits GPX4 activity. FINO2 is a stable oxidant that oxidizes ferrous iron and stable at varying pH levels. FINO2 causes widespread lipid peroxidation.
In Vitro Activity
FINO2 (10 µM; 24 h) induce ferroptosis and shows iron dependence of lipid peroxidation in HT-1080 cells.
Storage & Handling
Storage
4 °C, protect from light
In solvent : -80 °C, 6 months; -20 °C, 1 month (protect from light)
Shipping
Room temperature in continental US; may vary elsewhere.
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