Belongs to the peptidase M28 family. M28B subfamily.
Tissue Specificity
Predominantly expressed in liver.
Cellular Localization
Cell membrane, Cytoplasm and Membrane.
Function
Mediates cellular uptake of transferrin-bound iron in a non-iron dependent manner. May be involved in iron metabolism, hepatocyte function and erythrocyte differentiation (By similarity).
Disease Area
Hemochromatosis 3 (HFE3).
Storage & Handling
Storage
Store at -20 °C. Avoid repeated freeze-thaw cycles.
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