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Chrysosplenetin
Cat. No. IC23171
CAS. No. 603-56-5
Key Features and Details
Category
Inhibitor&Activator
Purity
99.75%
Formula
C19H18O8
Product Details
Product Name
Chrysosplenetin
CAS No.
603-56-5
Molecular Weight
374.34
Formula
C19H18O8
Appearance
Solid
Purity
99.75%
SMILES
O=C1C(OC)=C(C2=CC=C(O)C(OC)=C2)OC3=CC(OC)=C(OC)C(O)=C13
Product Overview
Description
Chrysosplenetin is one of the polymethoxylated flavonoids in Artemisia annua L. (Compositae) and other several Chinese herbs. Chrysosplenetin inhibits P-gp activity and reverses the up-regulated P-gp and MDR1 levels induced by artemisinin (ART). Chrysosplenetin significantly augments the rat plasma level and anti-malarial efficacy of ART, partially due to the uncompetitive inhibition effect of Chrysosplenetin on rat CYP3A.
Storage & Handling
Storage
4 °C, protect from light
In solvent : -80 °C, 6 months; -20 °C, 1 month (protect from light)
Shipping
Room temperature in continental US; may vary elsewhere.
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