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(E)-Ferulic acid-d3
Cat. No. IC23175
CAS. No. 860605-59-0
Key Features and Details
Category
Inhibitor&Activator
Purity
≥99.0%
Formula
C10H7D3O4
Product Details
Product Name
(E)-Ferulic acid-d3
CAS No.
860605-59-0
Molecular Weight
197.20
Synonyms
E-Coniferic acid-d3
Formula
C10H7D3O4
Appearance
Solid
Purity
≥99.0%
SMILES
O=C(O)/C=C/C1=CC=C(O)C(OC([2H])([2H])[2H])=C1
Product Overview
Description
(E)-Ferulic acid-d3 ((E)-Coniferic acid-d3) is the deuterium labeled (E)-Ferulic acid. (E)-Ferulic acid is a isomer of Ferulic acid which is an aromatic compound, abundant in plant cell walls. (E)-Ferulic acid causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pro-survival factor survivin. (E)-Ferulic acid shows a potent ability to remove reactive oxygen species (ROS) and inhibits lipid peroxidation. (E)-Ferulic acid exerts both anti-proliferation and anti-migration effects in the human lung cancer cell line H1299.
In Vitro Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Storage & Handling
Storage
Powder, -20 °C, 3 years; 4 °C, 2 years
In solvent: -80 °C, 6 months, -20 °C, 1 month.
Shipping
Room temperature in continental US; may vary elsewhere.
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