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Pioglitazone-d4 (alkyl)
Cat. No. IC23114
CAS. No. 1134163-31-7
Key Features and Details
Category
Inhibitor&Activator
Formula
C19H16D4N2O3S
Product Details
Product Name
Pioglitazone-d4 (alkyl)
CAS No.
1134163-31-7
Molecular Weight
360.46
Formula
C19H16D4N2O3S
SMILES
C(C1C(=O)NC(=O)S1)C2=CC=C(OC(C(C3=CC=C(CC)C=N3)([2H])[2H])([2H])[2H])C=C2
Product Overview
Description
Pioglitazone-d4 (alkyl) (U 72107-d4 (alkyl)) is the deuterium labeled Pioglitazone. Pioglitazone (U 72107) is a potent and selective PPARγ agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively.
In Vitro Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Storage & Handling
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping
Room temperature in continental US; may vary elsewhere.
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