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Pravastatin-13C,d3 Sodium
Cat. No. IC23189
CAS. No.
Key Features and Details
Category
Inhibitor&Activator
Formula
C2213CH32D3NaO7
Product Details
Product Name
Pravastatin-13C,d3 Sodium
Molecular Weight
450.52
Synonyms
CS-514-13C,d3 sodium
Formula
C2213CH32D3NaO7
SMILES
O[C@](C[C@@H](O)CC(O[Na])=O)([H])CC[C@@H]1[C@@]2([H])[C@H](C[C@@H](C=C2C=C[C@@H]1C)O)OC([C@@H]([13C]([2H])([2H])[2H])CC)=O
Product Overview
Description
Pravastatin-13C,d3 (sodium) is the 13C- and deuterium labeled Pravastatin (sodium). Pravastatin sodium (CS-514 sodium) is an HMG-CoA reductase inhibitor against sterol synthesis with IC50 of 5.6 μM.
In Vitro Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Storage & Handling
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping
Room temperature in continental US; may vary elsewhere.
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