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Troglitazone-d4
Cat. No. IC23088
CAS. No. 2749370-85-0
Key Features and Details
Category
Inhibitor&Activator
Formula
C24H23D4NO5S
Product Details
Product Name
Troglitazone-d4
CAS No.
2749370-85-0
Molecular Weight
445.56
Synonyms
CS-045-d4
Formula
C24H23D4NO5S
SMILES
O=C1SC(CC2=C([2H])C([2H])=C(C([2H])=C2[2H])OCC3(C)OC4=C(CC3)C(C)=C(O)C(C)=C4C)C(N1)=O
Product Overview
Description
Troglitazone-d4 is deuterium labeled Troglitazone. Troglitazone is a PPARγ agonist, with EC50s of 550 nM and 780 nM for human and murine PPARγ receptor, respectively.
In Vitro Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Storage & Handling
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping
Room temperature in continental US; may vary elsewhere.
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