Online Inquiry
Alogliptin-d3
Cat. No. IC23109
CAS. No. 1133421-35-8
Key Features and Details
Category
Inhibitor&Activator
Formula
C18H18D3N5O2
Product Details
Product Name
Alogliptin-d3
CAS No.
1133421-35-8
Molecular Weight
342.41
Synonyms
SYR-322-d3 free base
Formula
C18H18D3N5O2
SMILES
O=C(N(C1=O)C([2H])([2H])[2H])C=C(N2C[C@@H](CCC2)N)N1CC3=C(C=CC=C3)C#N
Product Overview
Description
Alogliptin-d3 (SYR-322-d3 (free base)) is the deuterium labeled Alogliptin. Alogliptin (SYR-322 free base) is a potent, selective and orally active inhibitor of DPP-4 with an IC50 of <10 nM, and exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9. Alogliptin can be used for the research of type 2 diabetes.
In Vitro Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Storage & Handling
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping
Room temperature in continental US; may vary elsewhere.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
Related Products