L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.
In Vitro Activity
L-Glutamic acid could act on [3H]DA release through presynaptic glutamatergic receptors. L-glutamic acid (50 μM) still stimulated the release of [3H] DA in the presence of tetrodotoxin (0.5 μM).
Storage & Handling
Storage
Powder, -20 °C, 3 years; 4 °C, 2 years
In solvent: -80 °C, 6 months, -20 °C, 1 month.
Shipping
Room temperature in continental US; may vary elsewhere.
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