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Artemisinin-d3
Cat. No. IC23177
CAS. No. 176652-07-6
Key Features and Details
Category
Inhibitor&Activator
Formula
C15H19D3O5
Product Details
Product Name
Artemisinin-d3
CAS No.
176652-07-6
Molecular Weight
285.35
Synonyms
Qinghaosu-d3; NSC 369397-d3
Formula
C15H19D3O5
SMILES
O=C1[C@H](C([2H])([2H])[2H])[C@]2([H])CC[C@@H](C)[C@]3([H])CC[C@@](O4)(C)OO[C@]32[C@]4([H])O1
Product Overview
Description
Artemisinin-d3 (Qinghaosu-d3) is the deuterium labeled Artemisinin. Artemisinin (Qinghaosu), a sesquiterpene lactone, is an anti-malarial drug isolated from the aerial parts of Artemisia annua L. plants. Artemisinin inhibits AKT signaling pathway by decreasing pAKT in a dose-dependent manner. Artemisinin reduces cancer cell proliferation, migration, invasion, tumorigenesis and metastasis and has neuroprotective effects.
In Vitro Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Storage & Handling
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping
Room temperature in continental US; may vary elsewhere.
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