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Rat Models

Why Are Rat Models Important for Drug Development?

  • Similarity of physiological functions. The physiological and biochemical processes of rats are very close to those of humans, which allows the results of drug tests performed on rats to speculate to some extent on their effects in humans.
  • Ease of manipulation. Compared to larger animal models, rats are easy and less expensive to raise and handle, facilitating extensive efficacy testing in the early stages of drug discovery.
  • Genetic Stability. The relatively stable genome of the rat makes it suitable for genetically related studies, which will provide opportunities to discover new drug targets in drug discovery.
  • Abundant models. Disease models based on rats are abundant and diverse, including but not limited to heart disease, diabetes, cancer, neurodegenerative diseases, etc., which is conducive to the screening and optimization of drugs in simulated disease environments.

Abundant Rat Models

Laboratory Rats

We have over 30,000 rat models in a wide variety of species, including rats, blind mole rats, sand rat, cotton rats, Nile grass rats, spiny rats, rice rat, diurnal Sudanese grass rat, South American water rat, long-tailed pygmy rice rat, and diurnal grass rat. They can be used to study a variety of diseases such as cancer, diabetes, Parkinson's disease, Alzheimer's disease, cardiovascular disease, depression, schizophrenia, autism, and more. By observing the lab rats, you can conduct more in-depth research on the pathogenesis of various diseases, pathological changes, drug efficacy and other studies.

Related Services

  • Customized disease model service. According to your research needs, we can provide genetic engineering model creation, disease animal model, xenograft model creation and genotyping services.
  • Disease model testing services. We can test the effects of specific drugs or treatments in disease models for you.
  • Rat model care and management services. Ensure that experimental animals grow in a favorable environment to ensure the accuracy of research results.
  • Professional consulting services. We provide free technical consultation and solutions to researchers conducting preclinical studies using animal models.

Related Models

Browse our list of rat models

Models Name Cat.No. Animal Type Disease Area
Gastrointestinal disorders (intestinal barrier dysfunction), transgenic (Abcb1-overexpressing)/parenteral nutrition-induced, in rat (Sprague Dawley) AB18120 rat Gastrointestinal Disorders
Gastrointestinal disorders, in rat (Sprague Dawley) AB18121 rat Gastrointestinal Disorders
Gastrointestinal injury, indomethacin-induced, in rat (Sprague Dawley) AB18122 rat Gastrointestinal injury
Gastrointestinal motility disorders, clonidine-induced, in rat (Sprague Dawley) AB18123 rat Gastrointestinal motility disorders
Gastrointestinal motility disorders, laparotomy-induced, in rat (Sprague Dawley) AB18124 rat Gastrointestinal motility disorders
Gastrointestinal mucosal dystrophies and secretion disorders, ethanol-induced, in rat (Sprague Dawley) AB18125 rat Gastrointestinal mucosal dystrophies and secretion disorders
Low back pain, intravertebral discs puncture-induced, in rat (Sprague Dawley) AB18126 rat Pain,low back
Lower urinary tract symptoms (LUTS), electrically-induced, in rat (Sprague Dawley) AB18127 rat Lower urinary tract symptoms (LUTS)
Lung cancer (adenocarcinoma), Il2rg +/-/Rag1/Rag2 knockout/patient-derived xenograft (Lung adenocarcinoma cells, human), in immunosuppressed rat (Sprague Dawley) AB18128 rat Cancer,lung
Lung cancer (non-small cell) (NSCLC) (large cell carcinoma), Il2rg +/- knockout/xenograft (NCI-H460), in immunosuppressed rat (Sprague Dawley) AB18129 rat Cancer,lung (non-small cell) (NSCLC) (large cell carcinoma)