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Please note that we are not a pharmacy or clinic, so we are unable to see patients and do not offer diagnostic and treatment services for individuals.

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Allergy Evaluation

Drug allergy is a reaction caused by drugs and is a special type of adverse drug reaction. Our company's allergy evaluation service is a simplified workflow by a group of specially trained and experienced scientists. We offer comprehensive services and technical support, designed to help our clients address possible barriers and challenges in rare disease therapy research and development.

Introduction to Allergy

Allergy refers to a specific immune response that manifests as tissue damage or physiological dysfunction after the body is re-stimulated by the same antigen. It is an abnormal or pathological immune response. Drug allergies generally occur after multiple exposures to the same drug. There is an incubation period for the first onset, but the recurrence can occur immediately. It occurs due to an abnormal immune response, which is generally harmful to the human body. Allergies are generally divided into four types.

Allergy

  • Type I

    Common symptoms:

    rash, itching, sneezing, runny nose, asthma attack, etc.

  • Type II

    Common symptoms:

    anemia, bleeding purpura, etc.

  • Type III

    Common symptoms:

    fever swollen lymph nodes, joint swelling and pain, kidney damage, etc.

  • Type IV

    Common symptoms:

    eczema, herpes, skin pigmentation, etc.

Animal Models for Allergy

Animal models are very important for allergy evaluation. They are the premise of screening allergens in drugs and the basis of preventing the occurrence of allergic reactions to drugs. Mice and rats are widely used in allergy evaluation. Among them, mice are commonly used as experimental animals for drug sensitization models due to their diverse immunological and molecular reactions. SD rats have the advantages of high sensitivity and good reproducibility. In addition, beagles, miniature pigs, and guinea pigs are also additional choices for allergic reaction research models.

Our Services

  • Design of Allergy Evaluation

Dose design

Multiple doses are generally selected, including the highest dose.

Statistical methods

Choose appropriate statistical methods based on the experimental model and test methods.

Control group

Establish a positive control group and a negative control group, or select a marketed preparation as a control.

  • Content of Allergy Evaluation
    Our company provides appropriate allergy evaluation services based on drug characteristics, indications, administration methods, occurrence mechanisms, influencing factors, etc.

Services we can provide include but are not limited to:

  • Active systemic anaphylaxis
  • Passive cutaneous anaphylaxis
  • Active cutaneous anaphylaxis
  • Skin photoallergy test
  • Guinea-pig maximization test
  • Buehler test
  • Murine local lymph node assay

Why Choose Us?

Hemolysis Evaluation
  • Customized services and products tailored to your research
  • Ph.D.-level scientists and skilled technicians
  • The rich experience accumulated in successful cases of new drug development
  • High data quality and reliable analysis
  • Fast and cost-efficient workflow
  • Expertise and experience in the industry

Project Workflow

Project Workflow

As an integrated CRO, our company provides clients with a cost-effective and convenient solution. Our allergy evaluation service is a simplified workflow by a group of specially trained and experienced scientists. We have the capabilities and resources to provide professional communication and problem-solving support to ensure that we can quickly respond to the changing needs of your rare disease therapy research projects. If you are interested in our services, please feel free to contact us for more information.

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

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