Cyclopeptide Development Platform
Cyclopeptide refers to a polypeptide chain with a cyclic ring structure. Our company has extensive expertise in therapeutic peptide development, particularly in cyclopeptide development, our platform has talented and experienced scientists who can provide professional cyclopeptide design solutions and services to ensure that we can quickly respond to the changing needs of your rare disease therapy research project.
Introduction to Cyclopeptides
Cyclopeptides generally refer to compounds formed by amino acid peptide bonds, containing alternating L and D amino acids. The final structure is stabilized by hydrogen bonds, which are arranged perpendicular to the ring. Cyclopeptides can be used for structural and biological function studies of polypeptides as well as enzyme function and kinetic studies. Cyclopeptides are diverse and have a variety of biological activities, including:
- Inhibit tyrosinase
- Inhibit cyclooxygenase
- Inhibit lipid peroxidase
- Inhibit platelet aggregation
Cyclopeptides for Rare Diseases
Cyclopeptides not only have diverse biological activities, but also have the advantages of stability and ease of synthesis, so they have wide applications in different fields such as the pharmaceutical industry, diagnosis, vaccine, and agricultural applications. Not only that, cyclopeptides also have broad application prospects in the field of rare disease research. There have been some cases of cyclopeptides being used in the treatment and research of rare diseases:
- Istodax for T-Cell Lymphoma
- Pasireotide for Cushing's Syndrome
- Setmelanotide for MC4R Deficiency
To increase the stability of peptides, our company provides cyclopeptide development services, thereby improving the pharmacological activity and stability of peptides and further accelerating your rare disease research.
- Types of Cyclopeptides
Our company uses different synthesis methods such as head-to-tail, head-to-side-chain, side-chain-to-side-chain, and side-chain-to-tail to provide you with the synthesis of cyclopeptides. The types of cyclopeptides we offer include but are not limited to:
|Head to Tail Cyclization
|Side chain to Side Chain
- Methods of Cyclopeptide Synthesis
With the continuous construction of the cyclopeptide development platform, we have more and more partners, and the methods of cyclopeptide synthesis have been improved, including:
- Phage display
- Individual synthesisu
- mRNA display
- Parallel synthesis
- Intein-based cyclopeptides
- Split-and-pool synthesis
- In silico screening
Why Choose Us?
- Ability to customize products and services
- Expertise and experience in the industry
- High data quality and reliable analysis
- Economical pricing and fast turnaround time
- Ph.D.-level scientists and skilled technicians
- Providing standardized upstream platform solutions
With many years of experience and a proven track record of quality, innovation, and customer support, our company provides comprehensive services for leading and emerging biopharmaceutical companies and scientific research institutions to develop cyclopeptides for rare diseases. If you are interested in our services, please feel free to contact us for more details and quotation information of related services.
- Claro, B., et al. "Design and applications of cyclopeptides." Peptide applications in biomedicine, biotechnology, and bioengineering. Woodhead Publishing, 2018. 87-129.
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.